Keto Diet Explained: Macros, Benefits, Risks (2026)
What Is the Ketogenic Diet?
The ketogenic (keto) diet is a very low carbohydrate, high fat dietary approach that shifts the body into a metabolic state called ketosis. In ketosis, your liver converts fatty acids into ketone bodies (primarily beta-hydroxybutyrate, acetoacetate, and acetone), which become the primary fuel source for the brain and muscles instead of glucose.
Standard keto macros: approximately 70% of calories from fat, 25% from protein, and 5% from carbohydrates — typically 20–50g of net carbs per day (net carbs = total carbs minus dietary fibre).
The Clinical Evidence
Weight loss: Meta-analyses consistently show keto produces rapid initial weight loss (largely water and glycogen) followed by fat loss comparable to other calorie-restricted diets over 12 months. The 2022 Annual Review of Nutrition concluded that keto offers no meaningful metabolic advantage over other diets when calories and protein are equated.
Type 2 diabetes: Some of the strongest evidence for keto. Studies show meaningful reductions in HbA1c, fasting glucose, and insulin requirements in people with type 2 diabetes following keto. Some participants have achieved remission.
Epilepsy: The original medical application of keto, developed in the 1920s. Still used today for drug-resistant epilepsy, particularly in children, where it can reduce seizure frequency by 50% or more in approximately half of patients.
Benefits of the Keto Diet
- Rapid initial weight loss (primarily glycogen and water, then fat)
- Reduced appetite — ketones and high fat/protein intake strongly suppress hunger hormones
- Improved blood glucose control in type 2 diabetes
- Reduced triglycerides in most people
- Potential neurological benefits — being actively researched for Alzheimer's, Parkinson's, and traumatic brain injury
Risks and Limitations
- Keto flu: Fatigue, headache, brain fog, and irritability during the first 1–2 weeks of adaptation. Caused by electrolyte shifts as insulin drops and kidneys excrete sodium and potassium.
- Elevated LDL cholesterol in some individuals, particularly with high saturated fat intake
- Micronutrient deficiencies if variety is limited — particularly magnesium, potassium, and B vitamins
- Athletic performance — keto impairs high-intensity exercise performance that relies on glycolysis
- Social difficulty and long-term adherence challenges
Frequently Asked Questions
References & Sources
- Bueno, N.B. et al. (2013). Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss. British Journal of Nutrition, 110(7), 1178–1187.
- Bolla, A.M. et al. (2019). Low-carb and ketogenic diets in type 1 and type 2 diabetes. Nutrients, 11(5), 962.
- Paoli, A. et al. (2013). Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate ketogenic diets. European Journal of Clinical Nutrition, 67(8), 789–796.